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Berkshire West Clinical Commissioning Group
 
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 Formulary Chapter 6: Endocrine system - Full Chapter
Notes:
This formulary is used by multiple organisations. There may be some instances where an item is on the formulary for one organisation but not the others. To help distinguish between each organisation, text will be colour coded, i.e. information relating to the Royal Berkshire NHS Foundation Trust will be in blue and Berkshire Healthcare NHS Foundation Trust will be in purple. Please ensure you read all information detailed under a drug.   
 Details...
06.01.02.03  Expand sub section  Other antidiabetic drugs
Dulaglutide (Trulicity®)
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Restricted Drug Restricted
Amber
Royal Berkshire NHS Foundation Trust >> Formulary Item pre-filled syringe / pre-filled pen Restricted Item  new initiations restricted to Consultant Endocrinologists ONLY


2nd line GLP-1 
Link  APC 129: Dulaglutide for type 2 DM
   
Empagliflozin  ((Jardiance))
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Formulary
Green
Royal Berkshire NHS Foundation Trust >> Formulary Item tablet
Restricted Item ONLY in line with NICE TA - link below

 
Link  APC 094 Empagliflozin for type 2 diabetes mellitus
Link  NICE TA - 336 - Empagliflozin in combination therapy for treating type 2 diabetes
Link  NICE TA 390 - Canagliflozin, dapagliflozin and empagliflozin as monotherapies for treating type 2 diabetes
   
Lixisenatide (Lyxumia)
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Formulary
Green
First choice GLP1
Approved by APC 1st May 2013. Ratified by GPMMC 10th July 2013.

Royal Berkshire NHS Foundation Trust >> Formulary Item subcutaneous injection
 
Link  APC 002: Lixisenatide (Lyxumia) for Type 2 Diabetes Mellitus
   
Acarbose (Glucobay®)
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Formulary
Green

Royal Berkshire NHS Foundation Trust >> Formulary Item tablets

Berkshire Healthcare NHS Foundation Trust >> Formulary Item tablets

 
   
Alogliptin (Vipidia®)
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Formulary
Green
Primary Care - First choice
DDP4 inhibitor of choice

Royal Berkshire NHS Foundation Trust >> Formulary Item tablets
 
Link  APC 025: Alogliptin for type 2 diabetes
Link  Risk of acute pancreatitis:MHRA update Sept 12
   
Canagliflozin  ((Invokana))
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Formulary
Green
Royal Berkshire NHS Foundation Trust >> Formulary Item tablets
Restricted Item ONLY in line with NICE TA - link below
 
Link  NICE TA 390 - Canagliflozin, dapagliflozin and empagliflozin as monotherapies for treating type 2 diabetes
Link  NICE TA 315: Canagliflozin in combination therapy for treating type 2 diabetes
   
Dapagliflozin (Forxiga ®)
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Formulary
Green
Royal Berkshire NHS Foundation Trust >> Formulary Item tablets
Restricted Item ONLY in line with NICE TA - link below


Berkshire Healthcare NHS Foundation Trust >> Formulary Item tablets
Restricted Item ONLY in line with NICE TA - link below
 
Link  NICE TA 418 - Dapagliflozin in triple therapy for treating type 2 diabetes
Link  NICE TA 390 - Canagliflozin, dapagliflozin and empagliflozin as monotherapies for treating type 2 diabetes
Link  NICE TA 288: Dapagliflozin in combination therapy for treating type 2 diabetes
   
Exenatide (Bydureon®)
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Formulary
Green
Thirdline for patients after lixisenatide or exenatide

Royal Berkshire NHS Foundation Trust >> Formulary Item subcutaneous injection
Restricted Item ONLY in line with NICE TA - link below
 
Link  NICE Guidelines - Type 2 diabetes in adults: management
   
Exenatide (Byetta®)
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Formulary
Green
2nd choice GLP1

Royal Berkshire NHS Foundation Trust >> Formulary Item subcutaneous injection
Restricted Item ONLY in line with NICE TA - link below
 
Link  MRHA warning on risk of acute pancreatitis and renal failure (2009)
Link  NICE Guidelines - Type 2 diabetes in adults: management
   
Linagliptin
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Formulary
Green
Royal Berkshire NHS Foundation Trust >> Formulary Item tablets

Restricted Item

 
Link  Risk of acute pancreatitis:MHRA update Sept 12
   
Liraglutide (Victoza®)
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Formulary
Green
Third choice for patients after lixisenatide and eventide

Royal Berkshire NHS Foundation Trust >> Formulary Item subcutaneous injection
Restricted Item ONLY in line with NICE TA - link below

 
Link  NICE Guideline - Type 2 diabetes in adults: management
   
Nateglinide (Starlix®)
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Formulary
Green
Royal Berkshire NHS Foundation Trust >> Formulary Item tablets
 
   
Pioglitazone (Actos®)
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Restricted Drug Restricted
Green
Royal Berkshire NHS Foundation Trust >> Formulary Item tablets - Restricted Item Restricted to use by the Diabetes Team ONLY
 
Link  Risk of bladder cancer: MHRA safety update
Link  Risk of cardiac failure when combined with insulin (MHRA safety update Jan 2011)
   
Sitagliptin (Januvia®)
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Formulary
Green
Royal Berkshire NHS Foundation Trust >> Formulary Item tablets
 
Link  Risk of acute pancreatitis:MHRA update Sept 12
   
 ....
 Non Formulary Items
Linagliptin/ metformin  (Jentadueto®)

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Non Formulary
Green
Royal Berkshire NHS Foundation Trust >> NON - Formulary Item - contact pharmacy for advice
Link  Risk of acute pancreatitis:MHRA update Sept 12
 
Metformin/saxagliptin  (Komboglyze®)

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Non Formulary
Brown
Royal Berkshire NHS Foundation Trust >> NON - Formulary Item - contact pharmacy for advice
Link  Risk of acute pancreatitis:MHRA update Sept 12
 
Pioglitazone and Metfomin  (Competact®)

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Non Formulary
Green
Royal Berkshire NHS Foundation Trust >> NON - Formulary Item - contact pharmacy for advice
 
Repaglinide  (Prandin®)

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Non Formulary
Green
Royal Berkshire NHS Foundation Trust >> NON - Formulary Item - contact pharmacy for advice
 
Rosiglitazone  (Avandia®)

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Non Formulary Royal Berkshire NHS Foundation Trust >> NON - Formulary Item - contact pharmacy for advice
Link  MHRA website
 
Rosiglitazone and Metformin  (Avandamet®)

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Non Formulary
Green
Royal Berkshire NHS Foundation Trust >> NON - Formulary Item - contact pharmacy for advice
 
Saxagliptin  (Onglyza®)

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Non Formulary
Green
Royal Berkshire NHS Foundation Trust >> NON - Formulary Item - contact pharmacy for advice
Link  Risk of acute pancreatitis. MHRA safety update Sept 12
Link  Serious hypersensitivity reactions & acute pancreatitis - Dear HCP Letter
 
Sitagliptin and Metformin  (Janumet®)

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Non Formulary
Green
Royal Berkshire NHS Foundation Trust >> NON - Formulary Item - contact pharmacy for advice
Link  Risk of acute pancreatitis:MHRA update Sept 12
 
Vildagliptin

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Non Formulary
Green
Royal Berkshire NHS Foundation Trust >> NON - Formulary Item - contact pharmacy for advice
Link  Risk of acute pancreatitis:MHRA update Sept 12
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Amber

Medicines that should be initiated or recommended by a specialist for continuation in primary care. The specialist must notify the primary care provider that the prescribing responsibility has been transferred. Where applicable, shared care protocols will be agreed and must be adhered to. The shared care protocol must have been agreed by the relevant secondary care trust Drugs and Therapeutics Committee(s)(DTC) and approved by Berkshire West APC.   

Brown

Drugs that have been reviewed and not recommended for prescribing. These drugs are not considered a cost effective use of scarce NHS resources. There may be individual patient specific or clinical reasons why a drug deemed low priority may be suitable for a particular patient. This is for the GP to condsider, weighing up the reasons against his/her allocated CCG budget. Where the decision is made to prescribe a low priority drug, detailed documentation must be included within the patients' notes for audit purposes. *Please note that low priority drug requests are unsuitable for the Case Review Committee and therefore should not be sent to this committee.   

Green

Medicines suitable for routine use and can be prescribed within primary care within their licensed indication in accordance with the BNF or other recognised national formulary. Primary care prescribers take full responsibility for prescribing  

Red

Medicines which should be prescribed by specialists only  

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