netFormulary Berkshire West NHS NHS
Royal Berkshire Foundation Trust
Berkshire Healthcare NHS Foundation Trust
Newbury and District CCG
North and West Reading CCG
South Reading CCG
Wokingham CCG
 
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 Formulary Chapter 14: Immunological products and vaccines - Full Section
Notes:

This formulary is used by multiple organisations. There may be some instances where an item is on the formulary for one organisation but not the others. To help distinguish between each organisation, text will be colour coded, i.e. information relating to the Royal Berkshire NHS Foundation Trust will be in blue and Berkshire Healthcare NHS Foundation Trust will be in purple. Please ensure you read all information detailed under a drug.  


Vaccines

Vaccines achieve active immunisation by stimulating an immune response. Vaccination should be postponed if patient is suffering from any infection except the common cold.

Vaccine types:

Live attenuated - live micro-organisms which have had their virulence reduced - e.g. rubella, measles, polio (oral polio vaccine), BCG.
If giving two separate live vaccines, either give simultaneously at different sites or with an interval of at least 3 weeks. Do not give live virus vaccine to a pregnant woman or immunosuppressed patient. A single dose of live vaccine usually confers immunity. 3 doses of polio are required.
Inactivated - inactive antigen - e.g. 'flu, typhoid, hepatitis B. A course of injections is required to produce an adequate antibody response. Booster injections are required. Extracts or detoxified exotoxins - from a micro-organism eg tetanus, diphtheria.

Immunoglobulins

For passive immunisation. Immunoglobulins confer immediate protection against certain infections, which lasts for a few weeks.

See BNF for information on childhood immunisation schedules and contra-indications.

Storage

Most vaccines must be refrigerated between 2 - 8(Oral polio 0 - 4oC)

Numbers in brackets indicate counts of (Formulary items, Non Formulary items)
14.01 Active immunity (0,0)
Immunisation schedule (0,0)
14.02 Passive immunity (0,0)
14.03 Storage and use (0,0)
14.04 Vaccines and antisera (0,1)
Anthrax vaccine (0,1)
BCG vaccines (2,0)
Botulism antitoxin (0,1)
Cholera vaccine (0,1)
Diphtheria vaccines (3,2)
Haemophilus influenzae type B vaccine (1,1)
Hepatitis A vaccine (0,8)
Hepatitis B vaccine (1,3)
Human papilloma virus vaccine (0,2)
Influenza vaccine (1,13)
Measles vaccine (0,0)
Measles, Mumps and Rubella (MMR) vaccine (1,0)
Meningococcal vaccines (3,2)
Mumps vaccine (0,0)
Pertussis vaccine (0,0)
Pneumococcal vaccines (2,1)
Poliomyelitis vaccines (1,1)
Rabies vaccine (0,2)
Rotavirus vaccine (1,0)
Rubella vaccine (0,0)
Smallpox vaccine (0,0)
Tetanus vaccines (0,1)
Tick-borne encephalitis vaccine (0,1)
Typhoid vaccines (0,4)
Varicella-zoster vaccine (0,3)
Yellow fever vaccine (0,1)
14.05 Immunoglobulins (0,0)
Normal immunoglobulin (0,2)
Specific immunoglobulins (0,1)
Anti-D (Rho) immunoglobulin (0,1)
Interferons (0,1)
14.05.01 Normal immunoglobulin (2,9)
14.05.02 Disease-specific immunoglobulins (3,1)
14.05.03 Anti-D (Rho) immunoglobulin (0,3)
14.06 International travel (0,0)
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